Harrison's Principles of Internal Medicine, Twentieth Edition (Vol.1 & Vol.2)

  • J. Larry Jameson Anthony S. Fauci Dennis L. Kasper
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MASTER MODERN MEDICINE! Introducing the Landmark Twentieth Edition of the Global Icon of Internal MedicineThe definitive guide to internal medicine is more essential than ever with the latest in disease mechanisms, updated clinical trial results and recommended guidelines, state-of-the art radiographic images, therapeutic approaches and specific treatments, hundreds of demonstrative full-color drawings, and practical clinical decision trees and algorithms Recognized by healthcare professionals worldwide as the leading authority on applied pathophysiology and clinical medicine, Harrison's Principles of Internal Medicine gives you the informational foundation you need to provide the best patient care possible. Essential for practice and education, the landmark 20th Edition features: Thoroughly revised content-covering the many new breakthroughs and advances in clinical medicine that have occurred since the last edition of Harrison's. Chapters on acute and chronic hepatitis, management of diabetes, immune-based therapies in cancer, multiple sclerosis, cardiovascular disease, HIV, and many more, deliver the very latest information on disease mechanisms, diagnostic options, and the specific treatment guidance you need to provide optimal patient care. State-of-the-art coverage of disease mechanisms: Harrison's focuses on pathophysiology with rigor, and with the goal of linking disease mechanisms to treatments. Improved understanding of how diseases develop and progress not only promotes better decision-making and higher value care, but also makes for fascinating reading and improved retention. Harrison's summarizes important new basic science developments, such as the role of mitochondria in programmed and necrotic cell death, the immune system's role in cancer development and treatment, the impact of telomere shortening in the aging and disease processes, and the role of the microbiome in health and disease. Understanding the role of inflammation in cardiovascular disease, the precise mechanisms of immune deficiency in HIV/AIDS, prions and misfolded proteins in neurodegenerative diseases, and obesity as a predisposition to diabetes are just a few examples of how this edition provides essential pathophysiology information for health professionals. All-new sections covering a wide range of new and emerging areas of vital interest to all healthcare professionals. New sections include: Sex and Gender-based Issues in Medicine; Obesity, Diabetes Mellitus, and Metabolic Syndrome; and Consultative Medicine- Plus, a new Part covering cutting-edge topics in research and clinical medicine includes great new chapters on the role of Epigenetics in Health and Disease, Behavioral Strategies to Improve Health, Genomics and Infectious Diseases, Emerging Neuro-Therapeutic Technologies, and Telomere Function in Health and Disease, and Network System Medicine. Important and timely new chapters-such as Promoting Good Health, LGBT Health, Systems of Healthcare, Approach to Medical Consultation, Pharmacogenomics, Antimicrobial Resistance, Worldwide Changes in Patterns of Infectious Diseases, Neuromyelitis Optica, and more-offer the very latest, definitive perspectives on must-know topics in medical education and practice. Updated clinical guidelines, expert opinions, and treatment approaches from world-renowned editors and authors contribute to the accuracy and immediacy of the text material and present a clear blueprint for optimizing patient outcomes. End-of-chapter suggested readings reinforc
CONTRIBUTORSPREFACEPart 1: The Profession of Medicine 1 The Practice of MedicineThe Editors 2 Promoting Good HealthDonald M. Lloyd-Jones, Kathleen M. McKibbin 3 Decision-Making in Clinical MedicineDaniel B. Mark, John B. Wong 4 Screening and Prevention of DiseaseKatrina A. Armstrong, Gary J. Martin 5 Health Care Systems in Developed CountriesRichard B. Saltman 6 The Safety and Quality of Health CareDavid W. Bates 7 Racial and Ethnic Disparities in Health CareJoseph R. Betancourt, Alexander R. Green 8 Ethical Issues in Clinical MedicineBernard Lo, Christine Grady 9 Palliative and End-of-Life CareEzekiel J. Emanuel Part 2: Cardinal Manifestations and Presentation of Diseases Section 1: Pain 10 Pain: Pathophysiology and ManagementJames P. Rathmell, Howard L. Fields 11 Chest DiscomfortDavid A. Morrow 12 Abdominal PainDanny O. Jacobs 13 HeadachePeter J. Goadsby 14 Back and Neck PainJohn W. Engstrom Section 2: Alterations in Body Temperature 15 FeverCharles A. Dinarello, Reuven Porat 16 Fever and RashElaine T. Kaye, Kenneth M. Kaye 17 Fever of Unknown OriginChantal P. Bleeker-Rovers, Jos W. M. van der Meer Section 3: Nervous System Dysfunction 18 SyncopeRoy Freeman 19 Dizziness and VertigoMark F. Walker, Robert B. Daroff 20 FatigueJeffrey M. Gelfand, Vanja C. Douglas 21 Neurologic Causes of Weakness and ParalysisMichael J. Aminoff 22 Numbness, Tingling, and Sensory LossMichael J. Aminoff 23 Gait Disorders, Imbalance and FallsJessica M. Baker, Lewis R. Sudarsky 24 Confusion and DeliriumS. Andrew Josephson, Bruce L. Miller 25 DementiaWilliam W. Seeley, Bruce L. Miller 26 Aphasia, Memory Loss, Hemispatial Neglect, Frontal Syndromes and Other Cerebral DisordersM.-Marsel Mesulam 27 Sleep DisordersThomas E. Scammell, Clifford B. Saper, Charles A. Czeisler Section 4: Disorders of Eyes, Ears, Nose, and Throat 28 Disorders of the EyeJonathan C. Horton 29 Disorders of Smell and TasteRichard L. Doty, Steven M. Bromley 30 Disorders of HearingAnil K. Lalwani 31 Sore Throat, Earache, and Upper Respiratory SymptomsMichael A. Rubin, Larry C. Ford, Ralph Gonzales 32 Oral Manifestations of DiseaseSamuel C. Durso Section 5: Alterations in Circulatory and Respiratory Functions 33 DyspneaRebecca M. Baron 34 Cough Christopher H. Fanta 35 HemoptysisAnna K. Brady, Patricia A. Kritek 36 Hypoxia and CyanosisJoseph Loscalzo 37 EdemaEugene Braunwald, Joseph Loscalzo 38 Approach to the Patient with a Heart MurmurPatrick T. O'Gara, Joseph Loscalzo 39 PalpitationsJoseph Loscalzo Section 6: Alterations in Gastrointestinal Function 40 DysphagiaIkuo Hirano, Peter J. Kahrilas 41 Nausea, Vomiting, and IndigestionWilliam L. Hasler 42 Diarrhea and ConstipationMichael Camilleri, Joseph A. Murray 43 Unintentional Weight LossJ. Larry Jameson 44 Gastrointestinal BleedingLoren Laine 45 JaundiceSavio John, Daniel S. Pratt 46 Abdominal Swelling and AscitesKathleen E. Corey, Lawrence S. Friedman Section 7: Alterations in Renal and Urinary Tract Function 47 Dysuria, Bladder Pain, and the Interstitial Cystitis/ Bladder Pain SyndromeJohn W. Warren 48 Azotemia and Urinary AbnormalitiesDavid B. Mount 49 Fluid and Electrolyte DisturbancesDavid B. Mount 50 Hypercalcemia and HypocalcemiaSundeep Khosla 51 Acidosis and AlkalosisThomas D. DuBose, Jr. Section 8: Alterations in the Skin 52 Approach to the Patient with a Skin DisorderKim B. Yancey, Thomas J. Lawley 53 Eczema, Psoriasis, Cutaneous Infections, Acne, and Other Common Skin DisordersLeslie P. Lawley, Calvin O. McCall, Thomas J. Lawley 54 Skin Manifestations of Internal DiseaseJean L. Bolognia, Irwin M. Braverman 55 Immunologically Mediated Skin DiseasesKim B. Yancey, Thomas J. Lawley 56 Cutaneous Drug ReactionsRobert G. Micheletti, Misha Rosenbach, Bruce U. Wintroub, Kanade Shinkai 57 Photosensitivity and Other Reactions to LightAlexander G. Marneros, David R. Bickers Section 9: Hematologic Alterations 58 Interpreting Peripheral Blood Smears Dan L. Longo 59 Anemia and PolycythemiaJohn W. Adamson, Dan L. Longo 60 Disorders of Granulocytes and MonocytesSteven M. Holland, John I. Gallin 61 Bleeding and ThrombosisBarbara A. Konkle 62 Enlargement of Lymph Nodes and SpleenDan L. Longo Part 3: Pharmacology 63 Principles of Clinical PharmacologyDan M. Roden 64 PharmacogenomicsDan M. Roden Part 4: Oncology and Hematology Section 1: Neoplastic Disorders 65 Approach to the Patient with CancerDan L. Longo 66 Prevention and Early Detection of CancerJennifer M. Croswell, Otis W. Brawley, Barnett S. Kramer 67 Cancer GeneticsFred Bunz, Bert Vogelstein 68 Cancer Cell BiologyJeffrey W. Clark, Dan L. Longo 69 Principles of Cancer TreatmentEdward A. Sausville, Dan L. Longo 70 Infections in Patients with CancerRobert W. Finberg 71 Oncologic EmergenciesRasim Gucalp, Janice P. Dutcher 72 Cancer of the SkinBrendan D. Curti, Sancy Leachman, Walter J. Urba 73 Head and Neck CancerEverett E. Vokes 74 Neoplasms of the LungLeora Horn, Christine M. Lovly 75 Breast CancerDaniel F. Hayes, Marc E. Lippman 76 Upper Gastrointestinal Tract CancersRobert J. Mayer 77 Lower Gastrointestinal CancersRobert J. Mayer 78 Tumors of the Liver and Biliary TreeJosep M. Llovet 79 Pancreatic CancerDaniel D. Von Hoff 80 Neuroendocrine Tumors of the Gastrointestinal Tract and PancreasRobert T. Jensen 81 Renal Cell CarcinomaRobert J. Motzer 82 Cancer of the Bladder and Urinary TractNoah M. Hahn 83 Benign and Malignant Diseases of the ProstateHoward I. Scher, James A. Eastham 84 Testicular CancerDavid J. Vaughn 85 Gynecologic MalignanciesDavid Spriggs 86 Primary and Metastatic Tumors of the Nervous SystemLisa M. DeAngelis, Patrick Y. Wen 87 Soft Tissue and Bone Sarcomas and Bone MetastasesShreyaskumar R. Patel 88 Carcinoma of Unknown PrimaryGauri R. Varadhachary, James L. Abbruzzese 89 Paraneoplastic Syndromes: Endocrinologic/HematologicJ. Larry Jameson, Dan L. Longo 90 Paraneoplastic Neurologic Syndromes and Autoimmune EncephalitisJosep Dalmau, Myrna R. Rosenfeld 91 Late Consequences of Cancer and Its TreatmentCarl E. Freter, Dan L. Longo Section 2: Hematopoietic Disorders 92 Hematopoietic Stem CellsDavid T. Scadden, Dan L. Longo 93 Iron Deficiency and Other Hypoproliferative Anem iasJohn W. Adamson 94 Disorders of HemoglobinEdward J. Benz, Jr. 95 Megaloblastic AnemiasA. Victor Hoffbrand 96 Hemolytic Anemias Lucio Luzzatto 97 Anemia Due to Acute Blood LossDan L. Longo 98 Bone Marrow Failure Syndromes Including Aplastic Anemia and MyelodysplasiaNeal S. Young 99 Polycythemia Vera and Other Myeloproliferative NeoplasmsJerry L. Spivak 100 Acute Myeloid LeukemiaWilliam Blum, Clara D. Bloomfield 101 Chronic Myeloid LeukemiaHagop Kantarjian, Jorge Cortes 102 Acute Lymphoid LeukemiaDieter Hoelzer 103 Chronic Lymphocytic LeukemiaJennifer A. Woyach, John C. Byrd 104 Non-Hodgkin's LymphomaCaron A. Jacobson, Dan L. Longo 105 Hodgkin's Lymphoma Caron A. Jacobson, Dan L. Longo 106 Less Common Hematologic MalignanciesAyalew Tefferi, Dan L. Longo 107 Plasma Cell DisordersNikhil C. Munshi, Dan L. Longo, Kenneth C. Anderson 108 AmyloidosisJohn L. Berk, Vaishali Sanchorawala 109 Transfusion Biology and TherapyJeffery S. Dzieczkowski, Pierre Tiberghien, Kenneth C. Anderson 110 Hematopoietic Cell TransplantationFrederick R. Appelbaum Section 3: Disorders of Hemostasis 111 Disorders of Platelets and Vessel WallBarbara A. Konkle 112 Coagulation DisordersValder R. Arruda, Katherine A. High 113 Arterial and Venous ThrombosisJane E. Freedman, Joseph Loscalzo 114 Antiplatelet, Anticoagulant, and Fibrinolytic DrugsJeffrey I. Weitz Part 5: Infectious Diseases Section 1: Basic Considerations in Infectious Diseases 115 Approach to the Patient with an Infectious DiseaseNeeraj K. Surana, Dennis L. Kasper 116 Molecular Mechanisms of Microbial PathogenesisGerald B. Pier 117 Approach to the Acutely Ill Infected Febrile PatientTamar F. Barlam, Dennis L. Kasper 118 Immunization Principles and Vaccine UseNancy Messonnier, Anne Schuchat, Lisa A. Jackson 119 Health Recommendations for International TravelJay S. Keystone, Phyllis E. Kozarsky 120 Climate Change and Infectious DiseaseAaron S. Bernstein Section 2: Clinical Syndromes: Community-Acquired Infections 121 PneumoniaLionel A. Mandell, Richard G. Wunderink 122 Lung AbscessRebecca M. Baron, Miriam Baron Barshak 123 Infective EndocarditisAdolf W. Karchmer 124 Infections of the Skin, Muscles, and Soft TissuesDennis L. Stevens 125 Infectious ArthritisLawrence C. Madoff 126 OsteomyelitisWerner Zimmerli 127 Intraabdominal Infections and AbscessesMiriam Baron Barshak, Dennis L. Kasper 128 Acute Infectious Diarrheal Diseases and Bacterial Food PoisoningRichelle C. Charles, Stephen B. Calderwood, Regina C. LaRocque 129 Clostridium difficile Infection, Including Pseudomembranous ColitisDale N. Gerding, Stuart Johnson 130 Urinary Tract Infections, Pyelonephritis, and ProstatitisKalpana Gupta, Barbara W. Trautner 131 Sexually Transmitted Infections: Overview and Clinical ApproachJeanne M. Marrazzo, King K. Holmes 132 EncephalitisKaren L. Roos, Kenneth L. Tyler 133 Acute MeningitisKaren L. Roos, Kenneth L. Tyler 134 Chronic and Recurrent MeningitisWalter J. Koroshetz, Michael R. Wilson, Avindra Nath 135 Brain Abscess and EmpyemaKaren L. Roos, Kenneth L. Tyler 136 Infectious Complications of BitesSandeep S. Jubbal, Florencia Pereyra, Lawrence C. Madoff Section 3: Clinical Syndromes: Health Care-Associated Infections 137 Infections Acquired in Health Care FacilitiesRobert A. Weinstein 138 Infections in Transplant RecipientsRobert W. Finberg, Joyce D. Fingeroth Section 4: Therapy for Bacterial Diseases 139 Treatment and Prophylaxis of Bacterial InfectionsDavid C. Hooper, Erica S. Shenoy, Christy A. Varughese 140 Bacterial Resistance to Antimicrobial AgentsDavid C. Hooper Section 5: Diseases Caused by Gram-Positive Bacteria 141 Pneumococcal InfectionsDavid Goldblatt, Katherine L. O'Brien 142 Staphylococcal InfectionsFranklin D. Lowy 143 Streptococcal InfectionsMichael R. Wessels 144 Enterococcal InfectionsCesar A. Arias, Barbara E. Murray 145 Diphtheria and Other Corynebacterial InfectionsWilliam R. Bishai, John R. Murphy 146 Listeria monocytogenes InfectionsElizabeth L. Hohmann, Daniel A. Portnoy 147 TetanusC. Louise Thwaites, Lam Minh Yen 148 BotulismAgam K. Rao, Susan Maslanka 149 Gas Gangrene and Other Clostridial InfectionsAmy E. Bryant, Dennis L. Stevens Section 6: Diseases Caused by Gram-Negative Bacteria 150 Meningococcal InfectionsAndrew J. Pollard 151 Gonococcal InfectionsSanjay Ram, Peter A. Rice 152 Haemophilus and Moraxella InfectionsTimothy F. Murphy 153 Infections Due to the HACEK Group and Miscellaneous Gram-Negative BacteriaTamar F. Barlam, Dennis L. Kasper 154 Legionella InfectionsVictor L. Yu, M. Luisa Pedro-Botet, Yusen E. Lin 155 Pertussis and Other Bordetella InfectionsKarina A. Top, Scott A. Halperin 156 Diseases Caused by Gram-Negative Enteric BacilliThomas A. Russo, James R. Johnson 157 Acinetobacter InfectionsRossana Rosa, L. Silvia Munoz-Price 158 Helicobacter pylori InfectionsJohn C. Atherton, Martin J. Blaser 159 Infections Due to Pseudomonas, Burkholderia, and Stenotrophomonas SpeciesReuben Ramphal 160 SalmonellosisDavid A. Pegues, Samuel I. Miller 161 ShigellosisPhilippe J. Sansonetti, Jean Bergounioux 162 Infections Due to Campylobacter and Related OrganismsBeth D. Kirkpatrick, Martin J. Blaser 163 Cholera and Other VibriosesMatthew K. Waldor, Edward T. Ryan 164 BrucellosisNicholas J. Beeching 165 TularemiaJeannine M. Petersen, Paul S. Mead 166 Plague and Other Yersinia InfectionsMichael B. Prentice 167 Bartonella Infections, Including Cat-Scratch DiseaseMichael Giladi, Moshe Ephros 168 DonovanosisNigel O'Farrell Section 7: Miscellaneous Bacterial Infections 169 NocardiosisGregory A. Filice 170 Actinomycosis Thomas A. Russo 171 Whipple's DiseaseThomas A. Russo 172 Infections Due to Mixed Anaerobic OrganismsNeeraj K. Surana, Dennis L. Kasper Section 8: Mycobacterial Diseases 173 TuberculosisMario C. Raviglione 174 LeprosyRobert H. Gelber 175 Nontuberculous Mycobacterial InfectionsSteven M. Holland 176 Antimycobacterial AgentsDivya Reddy, Max R. O'Donnell Section 9: Spirochetal Diseases 177 SyphilisSheila A. Lukehart 178 Endemic TreponematosesSheila A. Lukehart 179 LeptospirosisJiri F. P. Wagenaar, Marga G. A. Goris 180 Relapsing FeverAlan G. Barbour 181 Lyme BorreliosisAllen C. Steere Section 10: Diseases Caused by Rickettsiae, Mycoplasmas, and Chlamydiae 182 Rickettsial DiseasesDavid H. Walker, J. Stephen Dumler, Lucas S. Blanton, Thomas J. Marrie 183 Infections Due to MycoplasmasR. Doug Har dy 184 Chlamydial InfectionsCharlotte A. Gaydos, Thomas C. Quinn Section 11: Viral Diseases: General Considerations 185 Medical VirologyFred Wang, Elliott Kieff 186 Antiviral Chemotherapy, Excluding Antiretroviral DrugsLindsey R. Baden Section 12: Infections Due to DNA Viruses 187 Herpes Simplex Virus InfectionsLawrence Corey 188 Varicella-Zoster Virus InfectionsRichard J. Whitley 189 Epstein-Barr Virus Infections, Including Infectious MononucleosisJeffrey I. Cohen 190 Cytomegalovirus and Human Herpesvirus Types 6, 7, and 8Camille Nelson Kotton, Martin S. Hirsch 191 Molluscum Contagiosum, Monkeypox, and Other Poxvirus InfectionsFred Wang 192 Parvovirus InfectionsKevin E. Brown 193 Human Papillomavirus InfectionsDarron R. Brown, Aaron Ermel Section 13: Infections Due to DNA and RNA Respiratory Viruses 194 Common Viral Respiratory Infections James E. Crowe, Jr. 195 InfluenzaPeter F. Wright Section 14: Infections Due to Human Immunodeficiency Virus and Other Human Retroviruses 196 The Human RetrovirusesDan L. Longo, Anthony S. Fauci 197 Human Immunodeficiency Virus Disease: AIDS and Related DisordersAnthony S. Fauci, Gregory K. Folkers, H. Clifford Lane Section 15: Infections Due to RNA Viruses 198 Viral GastroenteritisUmesh D. Parashar, Roger I. Glass 199 Enterovirus, Parechovirus, and Reovirus InfectionsJeffrey I. Cohen 200 Measles (Rubeola)Kaitlin Rainwater-Lovett, William J. Moss 201 Rubella (German Measles)Laura A. Zimmerman, Susan E. Reef 202 MumpsSteven A. Rubin 203 Rabies and Other Rhabdovirus InfectionsAlan C. Jackson 204 Arthropod-Borne and Rodent-Borne Virus InfectionsJens H. Kuhn, Remi N. Charrel 205 Ebolavirus and Marburgvirus InfectionsJens H. Kuhn Section 16: Fungal Infections 206 Diagnosis and Treatment of Fungal InfectionsJohn E. Edwards, Jr. 207 HistoplasmosisChadi A. Hage, L. Joseph Wheat 208 CoccidioidomycosisNeil M. Ampel 209 BlastomycosisS. Travis King, Rathel L. Nolan, III 210 CryptococcosisArturo Casadevall 211 CandidiasisJohn E. Edwards, Jr. 212 AspergillosisDavid W. Denning 213 MucormycosisBrad Spellberg, Ashraf S. Ibrahim 214 Superficial Mycoses and Less Common Systemic MycosesCarol A. Kauffman 215 Pneumocystis InfectionsAlison Morris, Henry Masur Section 17: Protozoal and Helminthic Infections: General Considerations 216 Introduction to Parasitic Infections Sharon L. Reed, Charles E. Davis 217 Agents Used to Treat Parasitic InfectionsThomas A. Moore Section 18: Protozoal Infections 218 Amebiasis and Infection with Free-Living AmebaeRosa M. Andrade, Sharon L. Reed 219 MalariaNicholas J. White, Elizabeth A. Ashley 220 BabesiosisEdouard Vannier, Peter J. Krause 221 LeishmaniasisShyam Sundar 222 Chagas Disease and African TrypanosomiasisFrancois Chappuis, Yves Jackson 223 Toxoplasma InfectionsKami Kim 224 Protozoal Intestinal Infections and TrichomoniasisPeter F. Weller Section 19: Helminthic Infections 225 Introduction to Helminthic InfectionsPeter F. Weller 226 Trichinellosis and Other Tissue Nematode InfectionsPeter F. Weller 227 Intestinal Nematode InfectionsPeter F. Weller, Thomas B. Nutman 228 Filarial and Related InfectionsThomas B. Nutman, Peter F. Weller 229 Schistosomiasis and Other Trematode InfectionsBirgitte Jyding Vennervald 230 Cestode InfectionsA. Clinton White, Jr., Peter F. Weller Part 6: Disorders of the Cardiovascular System Section 1: Introduction to Cardiovascular Disorders 231 Approach to the Patient with Possible Cardiovascular DiseaseJoseph Loscalzo 232 Basic Biology of the Cardiovascular SystemJoseph Loscalzo, Peter Libby, Calum A. MacRae 233 Epidemiology of Cardiovascular DiseaseThomas A. Gaziano, J. Michael Gaziano Section 2: Diagnosis of Cardiovascular Disorders 234 Physical Examination of the Cardiovascular SystemPatrick T. O'Gara, Joseph Loscalzo 235 ElectrocardiographyAry L. Goldberger 236 Noninvasive Cardiac Imaging: Echocardiography, Nuclear Cardiology, and Magnetic Resonance/Computed Tomography ImagingMarcelo F. Di Carli, Raymond Y. Kwong, Scott D. Solomon 237 Diagnostic Cardiac Catheterization and Coronary AngiographyJane A. Leopold, David P. Faxon Section 3: Disorders of Rhythm 238 Principles of ElectrophysiologyDavid D. Spragg, Gordon F. Tomaselli 239 The Bradyarrhythmias: Disorders of the Sinoatrial NodeDavid D. Spragg, Gordon F. Tomaselli 240 The Bradyarrhythmias: Disorders of the Atrioventricular NodeDavid D. Spragg, Gordon F. Tomaselli 241 Approach to Supraventricular TachyarrhythmiasGregory F. Michaud, William G. Stevenson 242 Physiologic and Non-physiologic Sinus Tachycardia Gregory F. Michaud, William G. Stevenson 243 Focal Atrial Tachycardia Gregory F. Michaud, William G. Stevenson 244 Paroxysmal Supraventricular TachycardiasGregory F. Michaud, William G. Stevenson 245 Common Atrial Flutter, Macroreentrant and Multifocal Atrial TachycardiasGregory F. Michaud, William G. Stevenson 246 Atrial FibrillationGregory F. Michaud, William G. Stevenson 247 Approach to Ventricular Arrhythmias Roy M. John, William G. Stevenson 248 Premature Ventricular Beats, Non-sustained Ventricular Tachycardia, and Idioventricular Rhythm Roy M. John, William G. Stevenson 249 Sustained Ventricular Tachycardia William G. Stevenson, Roy M. John 250 Polymorphic Ventricular Tachycardia and Ventricular FibrillationWilliam G. Stevenson, Roy M. John 251 Electrical Storm and Incessant VTWilliam G. Stevenson, Roy M. John Section 4: Disorders of the Heart 252 Heart Failure: Pathophysiology and DiagnosisDouglas L. Mann, Murali Chakinala 253 Heart Failure: ManagementMandeep R. Mehra 254 Cardiomyopathy and MyocarditisNeal K. Lakdawala, Lynne Warner Stevenson, Joseph Loscalzo 255 Cardiac Transplantation and Prolonged Assisted Circulation Mandeep R. Mehra 256 Aortic Valve DiseasePatrick T. O'Gara, Joseph Loscalzo 257 Aortic Regurgitation Patrick T. O'Gara, Joseph Loscalzo 258 Mitral StenosisPatrick T. O'Gara, Joseph Loscalzo 259 Mitral RegurgitationPatrick T. O'Gara, Joseph Loscalzo 260 Mitral Valve ProlapsePatrick T. O'Gara, Joseph Loscalzo 261 Tricuspid Valve DiseasePatrick T. O'Gara, Joseph Loscalzo 262 Pulmonic Valve DiseasePatrick T. O'Gara, Joseph Loscalzo 263 Multiple and Mixed Valvular Heart DiseasePatrick T. O'Gara, Joseph Loscalzo 264 Congenital Heart Disease in the AdultAnne Marie Valente, Michael J. Landzberg 265 Pericardial DiseaseEugene Braunwald 266 Atrial Myxoma and Other Cardiac TumorsEric H. Awtry Section 5: Coronary and Peripheral Vascular Disease 267 Ischemic Heart DiseaseElliott Antman, Joseph Loscalzo 268 Non-ST-Segment Elevation Acute Coronary Syndrome (Non-ST-Segment Elevation Myocardial Infarction and Unstable Angina)Robert P. Giugliano, Christopher P. Cannon, Eugene Braunwald 269 ST-Segment Elevation Myocardial InfarctionElliott M. Antman, Joseph Loscalzo 270 Percutaneous Coronary Interventions and Other Interventional ProceduresDavid P. Faxon, Deepak L. Bhatt 271 Hypertensive Vascular DiseaseTheodore A. Kotchen 272 Renovascular DiseaseStephen C. Textor 273 Deep Venous Thrombosis and Pulmonary ThromboembolismSamuel Z. Goldhaber 274 Diseases of the AortaMark A. Creager, Joseph Loscalzo 275 Arterial Diseases of the ExtremitiesMark A. Creager, Joseph Loscalzo 276 Chronic Venous Disease and Lymphedema Mark A. Creager, Joseph Loscalzo 277 Pulmonary HypertensionAaron B. Waxman, Joseph Loscalzo Part 7: Disorders of the Respiratory System Section 1: Diagnosis of Respiratory Disorders 278 Approach to the Patient with Disease of the Respiratory SystemPatricia A. Kritek, Bruce D. Levy 279 Disturbances of Respiratory FunctionEdward T. Naureckas, Julian Solway 280 Diagnostic Procedures in Respiratory DiseaseAnne L. Fuhlbrigge, Augustine M.K. Choi Section 2: Diseases of the Respiratory System 281 AsthmaPeter J. Barnes 282 Hypersensitivity Pneumonitis and Pulmonary Infiltrates with EosinophiliaPraveen Akuthota, Michael E. Wechsler
Uitgavejaar 2018
ISBN 9781259644030
Verschijningsdatum 14 sep. 2018
Editie 20th edition
Auteur(s) J. Larry Jameson Anthony S. Fauci Dennis L. Kasper
Bindwijze Paperback
Taal Engels
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