Models, Molecules and Mechanisms in Biogerontology

  • Pramod C. Rath
€ 149,99
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  • Beschikbaar vanaf 15 maart 2020
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Beschrijving
The book deals with basic cellular and molecular mechanisms associated with aging. It comprehensively describes the important genetic, epigenetic, biochemical and metabolic regulations during aging, as well as some important age-related diseases.The book is divided into four major sections for easy understanding. It takes the readers through the various aspects of aging in a story-like manner. Certain interventions for healthy aging such as dietary restriction, regular exercise and maintaining a balanced and peaceful life-style are also suggested by the experts. The book would be a companion for both beginners, as well as established researchers in the field. It would be useful for science education, research, clinical approach and policy making.
Inhoudsopgave
I. Alterations in Cellular Mechanisms during Aging 1. Protein Structure and Function in Aging and Age-Related Diseases 2. DNA, DNA Replication and Aging 3. Transcription and Aging 4. Ribosomes, Translation and Aging 5. p53 and Aging 6. Paired box (Pax) Transcription Factors and Aging 7. Telomeres, Telomerase and Aging 8. The Epigenome of Ageing 9. Attaining Epigenetic Rejuvenation: Challenges Ahead 10. Mitochondria as a Key Player in Aging 11. Aging, Free Radicals and Reactive Oxygen Species: an Evolving Concept 12. Stem cells and Aging 13. Can autophagy stop the clock: Unravelling the mystery in Dictyostelium discoideum 14. Aging: Reading, Reasoning and Resolving using Drosophila as a Model System 15. Nothobranchius furzeri as a new model system for aging studies II. Alterations in Metabolism during Aging and Diseases 16. Aging in muscle 17. Metabolic Diseases and Aging 18. Interplay between Nutrient Sensing Molecules during Aging and Longevity
Vakgebieden
Productdetails
Uitgavejaar 2020
ISBN 9789813290044
Verschijningsdatum 15 mrt. 2020
Omvang 497
Editie 1st ed. 2020
Auteur(s) Pramod C. Rath
Bindwijze Gebonden
Taal Engels
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